Triparatide or Romozozumab

Hello all, I have been diagnosed with sever osteoporoses of spine and hip. I had a fracture of L2 only 6 months ago and I am told it has healed very well. I’ve seen two bone / osteoporosis specialist. I’ve been offered Teirparatide or Romozozumab injection, as I can’t take any meds orally. I am very worried and concerned about the side effect of these meds. Despite having stenosis of L4 & 5 and boldging disks I am fit and I walk everyday between 5km to 8km, anlso do wights at the gym, eat very healthy plus I take right supplements.terrifide taking meds as I don’t react very well with any medication. Any one here is on any of the meds I mentioned? if yes could you please let me know how you are coping and if you you’ve had positive result ? Much appreciate your feed back. Thanks

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Hi, finished a year’s course of Romozozunab in February. Apart from some local discomfort at the injection sites ,which I remedied by taking the injection out of the fridge the night before,I had no problem with this. I was apprehensive as I seem to react to a lot of medication,COVID,flu, shingles injections.

I started Romozozumab in February & have had no side effects. I take the injections out of the fridge the night before so that they are at room temperature. Yes, there is a little tenderness around the injection site lasting maybe 24 hours but no more than any other injection. I read recently on here that Dexa scan results showed 38% & 42% improvement for two individuals. Good luck.

Thanks for your replying.

I am totally against taking medication and until now at 67 always have used alternative medication for any health issue I’ve had, so it is really worrying having

been told I must take medication. I presume you would be put on a different medication going forward?

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I am happy I have joined this site . It is so comforting hearing other people’s experiences with the OS medication and the positive outcome. I was going to put my injection delivery on hold but I am feeling more confident. Ofcourse I am aware each individual react differently to side effect but knowing that some people are on OS medication and they are fine is helping me with my fear and worry that I had.

Thank you again :folded_hands:

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Hi very anti medication but have several health issues before being diagnosed with osteoporosis in January this year following a fall and a fracture. Refused more tablets and now had my second Denosumab jab. Had no side effects at all only pain is the price of a needle. Told I can stay on this for 5 years but GP always does full blood profile a week before

Hope this helps

Should say prick of the needle :rofl:

I too am currently on Romosozumab which I started in February. Like others I get mild irritation around the injection site lasting around 24 hrs and initially I was getting a headache for a couple of days after but I no longer get that 8 months in and haven’t for the last few months. I was nervous before embarking on this medication but not because I’m anti medication but more to do with the black box warning of very slight increase in risk of Stroke or Heart issues whilst on it. My Rheumatologist very astutely pointed out that my chances of further spinal fractures (I’ve had 7 already in my early 60’s) were statistically very much higher than my chances of Stroke or cardiac events. This very much put it into perspective for me and I then went forward feeling much happier with my decision. To be honest the excruciating pain and debilitation from the spinal fractures is something I never want to experience again and the long months of trying to get back to any sort of normality. Any medication that can help to lessen the chances of this has to be taken (for me anyway). The other thing that helped me to decide was the personal viewpoint that we are extremely lucky to be offered this medication if we meet the criteria for it. In other Countries such as America where women would desperately like to be offered it they find that even their private medical insurance won’t cover it and finally like others have said, the results from Romosozumab seem to be very promising so for me it was a bit of a no brainer. Good luck with your decision and hope this helps you to make the decision that is right for you.

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Thank you for taking time and answer my question. Yes it is very helpful. :folded_hands:

I injected teriparatide for 18 months with no side effects at all. My bone mass improved considerably and I now have 6- monthly injections of denosumab to maintain bone strength. Jill

Hi I’ve been on Evenity (Romoz…) for 6 months. The side effects started gradually but intensified by 4-6 months - itchy skin, headaches and joint pains (particularly where I have had fractures). I’m just hoping that this means it is working. Obviously different people will have different side effects or none at all.

Hi, I am taking the Teriparatide medication via injection - severe Osteoporosis and the only medication offered. Apart from having headaches in the first week or so, I haven’t had any side effects. I am on my 3rd month. Good luck with your decision. :purple_heart:

Thank you for your feedback back. Much appreciated .

Fibi

That’s what I’ve been offered( Triparatide) every day injection . But I saw a bone/ osteoporosis specialist privately, he recommended Romozozumab because it is a shorter duration.

That’s so comforting to know. Thanks for your feedback. I have already been offered Teripratide. How was your experience injecting every day?

I was scared at first but a nurse came to my home and talked me through it. I told her all my worries and she was great - offered comfort and stayed for over an hour. I practiced first and then did my own on myself. It is easy but it is all given step by step in the booklet you record everything in. The worst bit was finding a cool bag that will last long enough for my journey down south (from the north east). That was a major headache but the ladies in this site were extremely helpful!

Thanks for your feedback back :folded_hands:

Hi,

I’m not on medication yet but have been doing a lot of research.

I think that low hip bone density is more difficult to reverse than low spine bone density. So choosing a med could depend on your hip t score as some meds work better than others on the hips.

For instance I’ve heard that Romosozumab is good for hips (and spine) but increased risk of heart attack and stroke. But that Teriparatide while good for the spine is not as good for hips or forearm. This may be because it attacks cortical bone and the hips and forearm have more cortical bone than the spine.

Please don’t take what I’ve said as fact but it may be something to ask your practitioner if you have a choice of meds.

Good luck.

I wanted to be prescribed Romozozumab but the consultant refused, so I began my daily injections of Teriparatide three months ago. It has the advantage that it is a tried and tested drug and effective for strengthening the spine- I had a spinal fracture in February. I feared the side effects but after initial slight headaches, slight constipation and some achiness, everything has settled down I am very happy with the drug.

I inject immediately before bed and that works for me and prevents any problems with potential low blood pressure that can occur immediately after the injection. One interesting side effect is that I have to get up to urinate almost exactly 2 hours after the injection, but I am told that this demonstrates that my kidneys are working well. I am a good sleeper and fall back to sleep immediately after my WC visit. It is a small price to pay for what I hope will be a much stronger skeleton.

Dart Marybet , thanks for your feed back. Was there a reason you requested to have the Romozozumab?